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1

Neurotoxic properties of the anabolic androgenic steroids nandrolone and methandrostenolone in primary neuronal cultures

Filippo Caraci, V. Pistarà, A. Corsaro, Flora Tomasello, Maria Laura Giuffrida, Maria Angela Sortino, Ferdinando Nicoletti, Agata Copani

Journal:

Journal of Neuroscience Research

Year:

2011

Language:

english

File:

PDF, 1.08 MB

english, 2011

2

Design and synthesis of new trehalose-conjugated pentapeptides as inhibitors of Aβ(1–42) fibrillogenesis and toxicity

Paolo De Bona, Maria Laura Giuffrida, Filippo Caraci, Agata Copani, Bruno Pignataro, Francesco Attanasio, Sebastiano Cataldo, Giuseppe Pappalardo, Enrico Rizzarelli

Journal:

Journal of Peptide Science

Year:

2009

Language:

english

File:

PDF, 278 KB

english, 2009

3

The impact of metabotropic glutamate receptors into active neurodegenerative processes: A “dark side” in the development of new symptomatic treatments for neurologic and psychiatric disorders

Bruno, Valeria, Caraci, Filippo, Copani, Agata, Matrisciano, Francesco, Nicoletti, Ferdinando, Battaglia, Giuseppe

Journal:

Neuropharmacology

Year:

2016

Language:

english

File:

PDF, 1.30 MB

english, 2016

4

Functional partnership between mGlu3 and mGlu5 metabotropic glutamate receptors in the central nervous system

Di Menna, Luisa, Joffe, Max E., Iacovelli, Luisa, Orlando, Rosamaria, Lindsley, Craig W., Mairesse, Jèrome, Gressèns, Pierre, Cannella, Milena, Caraci, Filippo, Copani, Agata, Bruno, Valeria, Battagli

Journal:

Neuropharmacology

Year:

2017

Language:

english

File:

PDF, 3.62 MB

english, 2017

5

A major role for astrocytes in the neuroprotective effect of estrogen

Maria Angela Sortino, Paola Platania, Mariangela Chisari, Sara Merlo, Agata Copani, Maria Vincenza Catania

Journal:

Drug Development Research

Year:

2005

Language:

english

File:

PDF, 197 KB

english, 2005

6

Selective blockade of mGlu5 metabotropic glutamate receptors protects rat hepatocytes against hypoxic damage

Marianna Storto, Ugo de Grazia, Thomas Knöpfel, Pier Luigi Canonico, Agata Copani, Plinio Richelmi, Ferdinando Nicoletti, Mariapia Vairetti

Journal:

Year:

2000

Language:

english

File:

PDF, 367 KB

english, 2000

7

Aβ(25–35) and its C- and/or N-blocked derivatives: Copper driven structural features and neurotoxicity

Maria Laura Giuffrida, Giulia Grasso, Menotti Ruvo, Carlo Pedone, Angela Saporito, Daniela Marasco, Bruno Pignataro, Claudia Cascio, Agata Copani, Enrico Rizzarelli

Journal:

Journal of Neuroscience Research

Year:

2007

Language:

english

File:

PDF, 742 KB

english, 2007

8

Integrins mediate β-amyloid-induced cell-cycle activation and neuronal death

Giuseppina Frasca, Viviana Carbonaro, Sara Merlo, Agata Copani, Maria Angela Sortino

Journal:

Journal of Neuroscience Research

Year:

2008

Language:

english

File:

PDF, 233 KB

english, 2008

9

DNA polymerase-β mediates the neurogenic effect of β-amyloid protein in cultured subventricular zone neurospheres

Marco Calafiore, Agata Copani, Wenbin Deng

Journal:

Journal of Neuroscience Research

Year:

2012

Language:

english

File:

PDF, 489 KB

english, 2012

10

An activity-dependent switch from facilitation to inhibition in the control of excitotoxicity by group I metabotropic glutamate receptors

Valeria Bruno, Giuseppe Battaglia, Agata Copani, Virtudes M. Cespédes, María F. Galindo, Valentín Ceña, Jose Sánchez-Prieto, Fabrizio Gasparini, Rainer Kuhn, Peter J. Flor, Ferdinando Nicoletti

Journal:

European Journal of Neuroscience

Year:

2001

Language:

english

File:

PDF, 312 KB

english, 2001

11

Activation of Metabotropic Glutamate Receptors Prevents Neuronal Apoptosis in Culture

Agata Copani, Valeria M. G. Bruno, Vincenza Barresi, Giuseppe Battaglia, Daniele F. Condorelli, Ferdinando Nicoletti

Journal:

Journal of Neurochemistry

Year:

1995

Language:

english

File:

PDF, 1.04 MB

english, 1995

12

mGlu2 metabotropic glutamate receptors restrain inflammatory pain and mediate the analgesic activity of dual mGlu2/mGlu3 receptor agonists

Zammataro, Magda, Chiechio, Santina, Montana, Michael C, Traficante, Anna, Copani, Agata, Nicoletti, Ferdinando, Gereau, Robert W

Journal:

Year:

2011

Language:

english

File:

PDF, 283 KB

english, 2011

13

Dysfunction of TGF-β1 signaling in Alzheimer’s disease: perspectives for neuroprotection

Filippo Caraci, Simona Spampinato, Maria Angela Sortino, Paolo Bosco, Giuseppe Battaglia, Valeria Bruno, Filippo Drago, Ferdinando Nicoletti, Agata Copani

Journal:

Cell and Tissue Research

Year:

2012

Language:

english

File:

PDF, 285 KB

english, 2012

14

The Wnt Antagonist, Dickkopf-1, as a Target for the Treatment of Neurodegenerative Disorders

Filippo Caraci, Carla Busceti, Francesca Biagioni, Eleonora Aronica, Federica Mastroiacovo, Irene Cappuccio, Giuseppe Battaglia, Valeria Bruno, Andrea Caricasole, Agata Copani, Ferdinando Nicoletti

Journal:

Neurochemical Research

Year:

2008

Language:

english

File:

PDF, 297 KB

english, 2008

15

Inhibition of the canonical Wnt signaling pathway by apolipoprotein E4 in PC12 cells

Alessandra Caruso, Marta Motolese, Luisa Iacovelli, Filippo Caraci, Agata Copani, Ferdinando Nicoletti, Georg C. Terstappen, Giovanni Gaviraghi, Andrea Caricasole

Journal:

Journal of Neurochemistry

Year:

2006

Language:

english

File:

PDF, 261 KB

english, 2006

16

Activation of Pituitary Adenylate Cyclase-Activating Polypeptide Receptors Prevents Apoptotic Cell Death in Cultured Cerebellar Granule Cells

PIER LUIGI CANONICO, AGATA COPANI, VELIA D'AGATA, SIMONE MUSCO, SALVATORE PETRALIA, SALVATORE TRAVALI, FRANCA STIVALA, SEBASTIANO CAVALLARO

Journal:

Annals of the New York Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 151 KB

english, 1996

17

Metabotropic Glutamate Receptor Subtypes as Targets for Neuroprotective Drugs

Bruno, Valeria, Battaglia, Giuseppe, Copani, Agata, D'Onofrio, Mara, Di Iorio, P., De Blasi, Antonio, Melchiorri, Daniela, Flor, Peter J., Nicoletti, Ferdinando

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2001

Language:

english

File:

PDF, 724 KB

english, 2001

18

β-Amyloid-activated cell cycle in SH-SY5Y neuroblastoma cells

Giuseppina Frasca, Santina Chiechio, Carlo Vancheri, Ferdinando Nicoletti, Agata Copani, Maria Angela Sortino

Journal:

Journal of Molecular Neuroscience

Year:

2004

Language:

english

File:

PDF, 107 KB

english, 2004

19

Nicergoline, a drug used for age-dependent cognitive impairment, protects cultured neurons against β-amyloid toxicity

Filippo Caraci, Mariangela Chisari, Giuseppina Frasca, Pier Luigi Canonico, Angelo Battaglia, Marco Calafiore, Giuseppe Battaglia, Paolo Bosco, Ferdinando Nicoletti, Agata Copani, Maria Angela Sortino

Journal:

Year:

2005

Language:

english

File:

PDF, 499 KB

english, 2005

20

Depression and Alzheimer's disease: Neurobiological links and common pharmacological targets

Filippo Caraci, Agata Copani, Ferdinando Nicoletti, Filippo Drago

Journal:

European Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 255 KB

english, 2010

21

Inhibition of Wnt signaling, modulation of Tau phosphorylation and induction of neuronal cell death by DKK1

Carla Scali, Filippo Caraci, Marco Gianfriddo, Enrica Diodato, Renza Roncarati, Giuseppe Pollio, Giovanni Gaviraghi, Agata Copani, Ferdinando Nicoletti, Georg C. Terstappen, Andrea Caricasole

Journal:

Neurobiology of Disease

Year:

2006

Language:

english

File:

PDF, 1.56 MB

english, 2006

22

TGF-β1 protects against Aβ-neurotoxicity via the phosphatidylinositol-3-kinase pathway

Filippo Caraci, Giuseppe Battaglia, Carla Busceti, Francesca Biagioni, Federica Mastroiacovo, Paolo Bosco, Filippo Drago, Ferdinando Nicoletti, Maria Angela Sortino, Agata Copani

Journal:

Neurobiology of Disease

Year:

2008

Language:

english

File:

PDF, 1.26 MB

english, 2008

23

Enhanced expression of ERα in astrocytes modifies the response of cortical neurons to β-amyloid toxicity

Viviana Carbonaro, Filippo Caraci, Maria Laura Giuffrida, Sara Merlo, Pier Luigi Canonico, Filippo Drago, Agata Copani, Maria Angela Sortino

Journal:

Neurobiology of Disease

Year:

2009

Language:

english

File:

PDF, 942 KB

english, 2009

24

Neuroprotective activity of chemokines against N-methyl-d-aspartate or β-amyloid-induced toxicity in culture

Valeria Bruno, Agata Copani, Gilbert Besong, Giovanna Scoto, Ferdinando Nicoletti

Journal:

European Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 121 KB

english, 2000

25

Selective activation of group-II metabotropic glutamate receptors is protective against excitotoxic neuronal death

Giuseppe Battaglia, Valeria Bruno, Richard T Ngomba, Renato Di Grezia, Agata Copani, Ferdinando Nicoletti

Journal:

European Journal of Pharmacology

Year:

1998

Language:

english

File:

PDF, 129 KB

english, 1998

26

Hyperalgesic activity of kisspeptin in mice

Spampinato, Simona, Trabucco, Angela, Biasiotta, Antonella, Biagioni, Francesca, Cruccu, Giorgio, Copani, Agata, Colledge, William H, Sortino, Maria, Nicoletti, Ferdinando, Chiechio, Santina

Journal:

Year:

2011

Language:

english

File:

PDF, 1.05 MB

english, 2011

27

β-N-Methylamino-L-alanine (L-BMAA) is a potent agonist of ‘metabolotropic’ glutamate receptors

Agata Copani, Pier Luigi Canonico, Ferdinando Nicoletti

Journal:

European Journal of Pharmacology

Year:

1990

Language:

english

File:

PDF, 135 KB

english, 1990

28

Protective effect of the metabotropic glutamate receptor agonist, DCG-IV, against excitotoxic neuronal death

Valeria Bruno, Agata Copani, Giuseppe Battaglia, Rocco Raffaele, Huruiko Shinozaki, Ferdinando Nicoletti

Journal:

European Journal of Pharmacology

Year:

1994

Language:

english

File:

PDF, 293 KB

english, 1994

29

The nature of the cell cycle in neurons: Focus on a “non-canonical” pathway of DNA replication causally related to death

Agata Copani, Filippo Caraci, Jeroen J.M. Hoozemans, Marco Calafiore, Maria Angela Sortino, Ferdinando Nicoletti

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2007

Language:

english

File:

PDF, 177 KB

english, 2007

30

Astrocyte-like cells as a main target for estrogen action during neuronal differentiation

Sara Merlo, Marco Calafiore, Carlo Vancheri, Pier Luigi Canonico, Agata Copani, Maria-Angela Sortino

Journal:

Molecular and Cellular Neuroscience

Year:

2007

Language:

english

File:

PDF, 1.33 MB

english, 2007

31

Metabotropic glutamate receptors in neurodegeneration/neuroprotection: Still a hot topic?

Filippo Caraci, Giuseppe Battaglia, Maria Angela Sortino, Simona Spampinato, Gemma Molinaro, Agata Copani, Ferdinando Nicoletti, Valeria Bruno

Journal:

Neurochemistry International

Year:

2012

Language:

english

File:

PDF, 208 KB

english, 2012

32

The CDC2 I-G-T haplotype associated with the APOE ɛ4 allele increases the risk of sporadic Alzheimer's disease in Sicily

Paolo Bosco, Filippo Caraci, Agata Copani, Rosario S. Spada, Maria Angela Sortino, Roberto Salluzzo, Michele Salemi, Ferdinando Nicoletti, Raffaele Ferri

Journal:

Neuroscience Letters

Year:

2007

Language:

english

File:

PDF, 114 KB

english, 2007

33

Group I metabotropic glutamate receptors control proliferation, survival and differentiation of cultured neural progenitor cells isolated from the subventricular zone of adult mice

Marzia Castiglione, Marco Calafiore, Lara Costa, Maria Angela Sortino, Ferdinando Nicoletti, Agata Copani

Journal:

Neuropharmacology

Year:

2008

Language:

english

File:

PDF, 954 KB

english, 2008

34

Alzheimer's disease: brain expression of a metabolic disorder?

Sara Merlo, Simona Spampinato, Pier Luigi Canonico, Agata Copani, Maria Angela Sortino

Journal:

Trends in Endocrinology & Metabolism

Year:

2010

Language:

english

File:

PDF, 258 KB

english, 2010

35

Transcriptional regulation of type-2 metabotropic glutamate receptors: an epigenetic path to novel treatments for chronic pain

Santina Chiechio, Agata Copani, Magda Zammataro, Giuseppe Battaglia, Robert W. Gereau IV, Ferdinando Nicoletti

Journal:

Trends in Pharmacological Sciences

Year:

2010

Language:

english

File:

PDF, 535 KB

english, 2010

36

Genomic profiling of cortical neurons following exposure to β-amyloid

Sabrina Paratore, Rosalba Parenti, Antonietta Torrisi, Agata Copani, Federico Cicirata, Sebastiano Cavallaro

Journal:

Year:

2006

Language:

english

File:

PDF, 1.12 MB

english, 2006

37

The Wnt pathway, cell-cycle activation and β-amyloid: novel therapeutic strategies in Alzheimer's disease?

Andrea Caricasole, Agata Copani, Alessandra Caruso, Filippo Caraci, Luisa Iacovelli, Maria Angela Sortino, Georg C Terstappen, Ferdinando Nicoletti

Journal:

Trends in Pharmacological Sciences

Year:

2003

Language:

english

File:

PDF, 254 KB

english, 2003

38

Activation of cell-cycle-associated proteins in neuronal death: a mandatory or dispensable path?

Agata Copani, Agata Copani, Maria Angela Sortino, Ferdinando Nicoletti, Valeria Bruno, Ferdinando Nicoletti, Daniela Ubertia, Maurizio Memo

Journal:

Trends in Neurosciences

Year:

2001

Language:

english

File:

PDF, 113 KB

english, 2001

39

Effect of nitric oxide synthase induction on the expression of mitochondrial respiratory chain enzyme subunits in mixed cortical and astroglial cell cultures

Vincenzo G. Nicoletti, Alessandra Caruso, Elisabetta A. Tendl, Antonia Privitera, Antonella Console, Vittorio Calabrese, Filippo Spadaro, Agrippino Ravagna, Agata Copani, Anna Maria Giuffrida Stella

Journal:

Year:

1998

Language:

english

File:

PDF, 2.30 MB

english, 1998

40

TGF-β1 Pathway as a New Target for Neuroprotection in Alzheimer's Disease

Filippo Caraci, Giuseppe Battaglia, Valeria Bruno, Paolo Bosco, Viviana Carbonaro, Maria Laura Giuffrida, Filippo Drago, Maria Angela Sortino, Ferdinando Nicoletti, Agata Copani

Journal:

CNS Neuroscience & Therapeutics

Year:

2011

Language:

english

File:

PDF, 279 KB

english, 2011

41

Beta-Amyloid Monomer and Insulin/IGF-1 Signaling in Alzheimer's Disease

Giuffrida, Maria Laura, Tomasello, Flora, Caraci, Filippo, Chiechio, Santina, Nicoletti, Ferdinando, Copani, Agata

Journal:

Molecular Neurobiology

Year:

2012

Language:

english

File:

PDF, 238 KB

english, 2012

42

TGF-β1 targets the GSK-3β/β-catenin pathway via ERK activation in the transition of human lung fibroblasts into myofibroblasts

Filippo Caraci, Elisa Gili, Marco Calafiore, Marco Failla, Cristina La Rosa, Nunzio Crimi, Maria Angela Sortino, Ferdinando Nicoletti, Agata Copani, Carlo Vancheri

Journal:

Pharmacological Research

Year:

2008

Language:

english

File:

PDF, 794 KB

english, 2008

43

Fingolimod protects cultured cortical neurons against excitotoxic death

Luisa Di Menna, Gemma Molinaro, Luigi Di Nuzzo, Barbara Riozzi, Cristina Zappulla, Carlo Pozzilli, Renato Turrini, Filippo Caraci, Agata Copani, Giuseppe Battaglia, Ferdinando Nicoletti, Valeria Bruno

Journal:

Pharmacological Research

Year:

2013

Language:

english

File:

PDF, 691 KB

english, 2013

44

Metabotropic glutamate receptor agonists stimulate polyphosphoinositide hydrolysis in primary cultures of rat hepatocytes

Francesc Sureda, Agata Copani, Valeria Bruno, Thomas Knöpfel, Gainer Meltzger, Ferdinando Nicoletti

Journal:

European Journal of Pharmacology

Year:

1997

Language:

english

File:

PDF, 51 KB

english, 1997

45

Transcriptional regulation of metabotropic glutamate receptor 2/3 expression by the NF-κB pathway in primary dorsal root ganglia neurons: a possible mechanism for the analgesic effect of L-acetylcarnitine

Santina Chiechio, Agata Copani, Laura De Petris, Maria Elena P Morales…

Journal:

Year:

2006

Language:

english

File:

PDF, 1.03 MB

english, 2006

46

Î²-Amyloid neurotoxicity: A discussion of in vitro findings

Cotman, Carl W., Pike, Christian J., Copani, Agata

Journal:

Neurobiology of Aging

Year:

1992

Language:

english

File:

PDF, 456 KB

english, 1992

47

A ratiometric naphthalimide sensor for live cell imaging of copper(i)

Satriano, Cristina, Sfrazzetto, Giuseppe Trusso, Amato, Maria Emanuela, Ballistreri, Francesco P., Copani, Agata, Giuffrida, Maria Laura, Grasso, Giuseppe, Pappalardo, Andrea, Rizzarelli, Enrico, Toma

Journal:

Chemical Communications

Year:

2013

Language:

english

File:

PDF, 2.17 MB

english, 2013

48

Protective action of idebenone against excitotoxic degeneration in cultured cortical neurons

Bruno, Valeria, Battaglia, Giuseppe, Copani, Agata, Sortino, Maria Angela, Canonico, Pier Luigi, Nicoletti, Ferdinando

Journal:

Neuroscience Letters

Year:

1994

Language:

english

File:

PDF, 348 KB

english, 1994

49

Acetyl-L-Carnitine in Neuropathic Pain

Chiechio, Santina, Copani, Agata, Gereau, Robert W, Nicoletti, Ferdinando

Journal:

Year:

2007

Language:

english

File:

PDF, 123 KB

english, 2007

50

Insulin Has Multiple Antiamyloidogenic Effects on Human Neuronal Cells

Pandini, Giuseppe, Pace, Vincenza, Copani, Agata, Squatrito, Sebastiano, Milardi, Danilo, Vigneri, Riccardo

Journal:

Year:

2013

Language:

english

File:

PDF, 1020 KB

english, 2013